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Chemical structure of CAS 57333-96-7

Tacalcitol

In Stock•Starting at $171 for 1 mg•Purity ≥ 98%
CAS No.57333-96-7
MDL No.MFCD13184757
MFC27H44O3
MW416.60
InChI KeyBJYLYJCXYAMOFT-RSFVBTMBSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mg≥98%$171In Stock
5 mg≥98%$718In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Tacalcitol is a hydroxy seco-steroid and vitamin D3 analog with hydroxy groups at positions 1S and 24R. It is used to treat psoriasis vulgaris in adults, particularly on the scalp. It functions as an antipsoriatic, vitamin D receptor agonist, and antineoplastic agent. It belongs to D3 vitamins, hydroxy seco-steroids, secondary alcohols, and seco-cholestanes, and is functionally related to calciol.

CAS No.57333-96-7
Product NameTacalcitol

Associated Conditions

psoriasis vulgaris·psoriasis
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Motor neuron-like NSC-34 cells as a new model for the study of vitamin D metabolism in the brain.

The Journal of steroid biochemistry and molecular biology • Vol. 158 • 2016
PMID: 26704532DOI: 10.1016/j.jsbmb.2015.12.010

Hypercalcemia caused by vitamin D3 analogs in psoriasis treatment.

International journal of dermatology • Vol. 46, Issue 12 • 2007
PMID: 18173537DOI: 10.1111/j.1365-4632.2007.03347.x

Does the determination of the Bb vitamin D receptor genotype identify psoriasis vulgaris patients responsive to topical tacalcitol?

Journal of dermatological science • Vol. 37, Issue 3 • 2005
PMID: 15734288DOI: 10.1016/j.jdermsci.2004.11.008

Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat.

Brain research • Vol. 1039, Issue 1-2 • 2005
PMID: 15781040DOI: 10.1016/j.brainres.2005.01.034

Documentation

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