Nucleic Acid Synthesis & Conjugation Materials

Find monomers, nucleotides and GalNAc building blocks for your synthesis workflow. Browse the material families and request specifications for the exact structure and quantity you need.

Oligonucleotide Building Blocks

Browse by sugar modification, protecting group or monomer type. Exact base protection and stereochemistry should be specified with the requested structure.

2′-OMe Phosphoramidites

6 products

2′-O-methyl A, U, G and C monomers, with additional protecting-group and modified-base options listed in the catalog.

  • 2′-OMe-Bz-A Phosphoramidite

    DC-R0120 · CAS 110782-31-5

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 2′-OMe-U Phosphoramidite

    DC-R0121 · CAS 110764-79-9

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 2′-OMe-ibu-G Phosphoramidite

    DC-R0122 · CAS 150780-67-9

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 2′-OMe-Ac-C Phosphoramidite

    DC-R0123 · CAS 199593-09-4

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 2′-OMe-PAc-A Phosphoramidite

    DC-R0124 · CAS 145520-30-5

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • DMT-2′-OMe-Pseudouridine-CE-Phosphoramidite

    DC-R0125 · CAS 199737-09-2

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote

2′-F Phosphoramidites

6 products

2′-fluoro A, U, G and C monomers. Specify the base protection and phosphoramidite form when requesting a quotation.

  • 2′-F-dA(Bz)-CE Phosphoramidite

    DC-R0126 · CAS 136834-22-5

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 2′-F-dU-CE Phosphoramidite

    DC-R0127 · CAS 146954-75-8

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 2′-F-dG(ibu)-CE Phosphoramidite

    DC-R0128 · CAS 144089-97-4

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 2′-F-Ac-dC-CE-Phosphoramidite

    DC-R0129 · CAS 159414-99-0

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 2′-F-dA(Bz)-CE-Methyl Phosphoramidite

    DC-R0130

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 2′-F-dA(PAc)-CE Phosphoramidite

    DC-R0131

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote

DNA Phosphoramidites

6 products

Deoxynucleoside A, T, G and C phosphoramidites with catalog-listed base-protection variants.

  • DMT-dA(Bz)-CE-Phosphoramidite

    DC-R0132 · CAS 98796-53-3

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • DMT-dT-CE-Phosphoramidite

    DC-R0133 · CAS 98796-51-1

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • DMT-dG(dmf)-CE-Phosphoramidite

    DC-R0134 · CAS 330628-04-1

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • DMT-dG(ibu)-CE-Phosphoramidite

    DC-R0135 · CAS 93183-15-4

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • DMT-dC(Ac)-CE-Phosphoramidite

    DC-R0136 · CAS 154110-40-4

    Product details
    Catalog packs
    10 g, 100 g, kg quantities

    The catalog uses this name for two entries with different CAS numbers and structures. Specify the required structure and CAS number.

    Request quote
  • DMT-dC(Ac)-CE-Phosphoramidite

    DC-R0137 · CAS 102212-98-6

    Product details
    Catalog packs
    10 g, 100 g, kg quantities

    The catalog uses this name for two entries with different CAS numbers and structures. Specify the required structure and CAS number.

    Request quote

3′-Amino Phosphoramidites

4 products

3′-NH-Tr-protected A, T, G and C monomers with a 5′-phosphoramidite group.

  • 3′-NH-Tr-2′,3′-ddA(dmf)-5′-CE Phosphoramidite

    DC-R0138 · CAS 1644649-86-4

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 3′-NH-Tr-2′,3′-ddT-5′-CE Phosphoramidite

    DC-R0139 · CAS 195375-68-9

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 3′-NH-Tr-2′,3′-ddG(iBu)-5′-CE Phosphoramidite

    DC-R0140 · CAS 195375-66-7

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 3′-NH-Tr-2′,3′-ddC(Bz)-5′-CE Phosphoramidite

    DC-R0141 · CAS 195375-65-6

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote

2′-MOE Phosphoramidites

4 products

2′-O-methoxyethyl A, U, G and C monomers for projects requiring this sugar modification.

  • 2′-O-MOE-A(Bz)-3′-phosphoramidite

    DC-R0142 · CAS 251647-53-7

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 2′-O-MOE-U Phosphoramidite

    DC-R0143 · CAS 163759-97-5

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 2′-MOE-G(iBu)-3′-phosphoramidite

    DC-R0144 · CAS 251647-55-9

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 2′-O-MOE-Bz-C Phosphoramidite

    DC-R0145 · CAS 251647-54-8

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote

2′-O-TBDMS RNA Phosphoramidites

4 products

TBDMS-protected A, U, G and C ribonucleoside phosphoramidites.

  • DMT-2′-O-TBDMS-A(Bz)-CE-Phosphoramidite

    DC-R0146 · CAS 104992-55-4

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • DMT-2′-O-TBDMS-U-CE-Phosphoramidite

    DC-R0147 · CAS 118362-03-1

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • DMT-2′-O-TBDMS-G(iBu)-CE-Phosphoramidite

    DC-R0148 · CAS 147201-04-5

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • DMT-2′-O-TBDMS-C(Ac)-CE-Phosphoramidite

    DC-R0149 · CAS 121058-88-6

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote

5′-(S)-C-Methyl Phosphoramidites

8 products

5′-(S)-C-methyl monomers with catalog-listed 2′-OMe and 2′-F variants.

  • 5′-(S)-C-Me-5′-ODMTr-2′-OMe-dA(Bz)-CNE-phosphoramidite

    DC-R0150

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 5′-(S)-C-Me-5′-ODMTr-2′-OMe-dU-CNE-phosphoramidite

    DC-R0151 · CAS 2747890-15-7

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 5′-(S)-C-Me-5′-ODMTr-2′-OMe-dG(ibu)-CNE-phosphoramidite

    DC-R0152

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 5′-(S)-C-Me-5′-ODMTr-2′-OMe-dC(Ac)-CNE-phosphoramidite

    DC-R0153 · CAS 1883486-16-5

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 5′-(S)-C-Me-5′-ODMTr-2′-F-dA(Bz)-CNE-phosphoramidite

    DC-R0154

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 5′-(S)-C-Me-5′-ODMTr-2′-F-dU-CNE-phosphoramidite

    DC-R0155 · CAS 1047658-69-4

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 5′-(S)-C-Me-5′-ODMTr-2′-F-dG(iBu)-CNE-phosphoramidite

    DC-R0156

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 5′-(S)-C-Me-5′-ODMTr-2′-F-dC(Ac)-CNE-phosphoramidite

    DC-R0157 · CAS 1883486-17-6

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote

PMO Monomers

4 products

Morpholino A, T, G and C subunits. Share the target subunit and required specification for technical review.

  • Morpholino A subunit

    DC-R0158 · CAS 956139-18-7

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • Morpholino T subunit

    DC-R0159 · CAS 956139-30-3

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • Morpholino G subunit

    DC-R0160 · CAS 956139-25-6

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • Morpholino C subunit

    DC-R0161 · CAS 956139-21-2

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote

Other Modified Monomers & Dimers

6 products

Catalog examples include AmAf, UmUm and AmAm dimers, a vinylphosphonate monomer and 2′-OCF₃ monomers.

  • AmAf dimer

    DC-R0162

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • UmUm dimer

    DC-R0163

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • AmAm dimer

    DC-R0164

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 5′-POM-(E)-vinyl phosphonate-2′-O-Me-rU-3′-CE-Phosphoramidite

    DC-R0165 · CAS 2172373-55-4

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 2′-OCF3-Bz-C Phosphoramidite

    DC-R0166

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote
  • 2′-OCF3-iBu-G Phosphoramidite

    DC-R0167

    Product details
    Catalog packs
    10 g, 100 g, kg quantities
    Request quote

GalNAc Ligands & Building Blocks

Explore named GalNAc ligands, phosphoramidites and loaded supports, alongside advanced intermediates and linker options.

Browse GalNAc materials

mRNA Synthesis Reagents

Review nucleotide, modified-nucleoside and cap-analog families. Include concentration, counterion and formulation requirements in your inquiry.

Nucleoside Triphosphates (NTPs)

6 products

ATP, UTP, GTP and CTP listed as 100 mM sodium solutions, plus an NTP mix and a Tris-solution option.

  • ATP, 100 mM Sodium Solution

    DC-R0168 · CAS 20978-32-9

    Product details
    Catalog packs
    1 mL, 10 mL, 100 mL
    Request quote
  • UTP, 100 mM Sodium Solution

    DC-R0169 · CAS 19817-92-6

    Product details
    Catalog packs
    1 mL, 10 mL, 100 mL
    Request quote
  • GTP, 100 mM Sodium Solution

    DC-R0170 · CAS 36051-31-7

    Product details
    Catalog packs
    1 mL, 10 mL, 100 mL
    Request quote
  • CTP, 100 mM Sodium Solution

    DC-R0171 · CAS 54619-78-2

    Product details
    Catalog packs
    1 mL, 10 mL, 100 mL
    Request quote
  • NTP MIX, 25 mM sodium solution each

    DC-R0172

    Product details
    Catalog packs
    1 mL, 10 mL, 100 mL
    Request quote
  • NTP, 100 mM Tris Solution

    DC-R0173

    Product details
    Catalog packs
    1 mL, 10 mL, 100 mL
    Request quote

Pseudouridine & N1-Methylpseudouridine

3 products

Pseudouridine, N1-methylpseudouridine and N1-methylpseudouridine triphosphate (N1-Me-pUTP).

  • Pseudouridine

    DC-R0174 · CAS 1445-07-4

    Product details
    Catalog packs
    g and kg quantities
    Request quote
  • N1-Me-Pseudouridine

    DC-R0175 · CAS 13860-38-3

    Product details
    Catalog packs
    g and kg quantities
    Request quote
  • N1-Me-pUTP, 100 mM Sodium Solution

    DC-R0176 · CAS 1428903-59-6

    Product details
    Catalog packs
    1 mL, 10 mL, 100 mL
    Request quote

Modified NTPs

6 products

Catalog examples include 5-Me-CTP, 5-AA-UTP, 5-OMe-UTP, 3′-OMe-GTP, 2-F-ATP and 5-Me-UTP.

  • 5-Me-CTP

    DC-R0177 · CAS 327174-86-7

    Product details
    Catalog packs
    1 mL, 10 mL, 100 mL
    Request quote
  • 5-AA-UTP

    DC-R0178 · CAS 161441-79-8

    Product details
    Catalog packs
    1 mL, 10 mL, 100 mL
    Request quote
  • 5-OMe-UTP

    DC-R0179 · CAS 847649-65-4

    Product details
    Catalog packs
    1 mL, 10 mL, 100 mL
    Request quote
  • 3′-OMe-GTP

    DC-R0180

    Product details
    Catalog packs
    1 mL, 10 mL, 100 mL
    Request quote
  • 2-F-ATP

    DC-R0181

    Product details
    Catalog packs
    1 mL, 10 mL, 100 mL
    Request quote
  • 5-Me-UTP

    DC-R0182 · CAS 23198-01-8

    Product details
    Catalog packs
    1 mL, 10 mL, 100 mL
    Request quote

Cap Analogs

2 products

CAP GAG and CAP GAG (3′OMe) forms are listed. Include the exact cap structure and formulation in your request.

  • CAP GAG: m7G(5′)ppp(5′)(2′OMeA)pG

    DC-R0183

    Product details
    Catalog packs
    100 μL, 1 mL, 10 mL, 100 mL
    Request quote
  • CAP GAG (3′OMe): m7(3′OMeG)(5′)ppp(5′)(2′OMeA)pG

    DC-R0184

    Product details
    Catalog packs
    100 μL, 1 mL, 10 mL, 100 mL
    Request quote
Oligonucleotide synthesis resins

Continue to primer, nucleotide-loaded and specialized solid supports. Request the loading and support configuration needed for your workflow.

Have a non-catalog target?

Share a target structure and specification for a custom synthesis assessment. Feasibility is reviewed for the individual compound.

Discuss your material requirements

Include the product name or structure, modification, quantity and required delivery date. Product-specific specifications, documentation and supply timing are confirmed during quotation.

DISCUSS YOUR REQUIREMENTS