API & Candidates

Abacavir hydroxyacetate is a salt form of Abacavir, which blocks viral replication by inhibiting the reverse transcriptase of the Human immunodeficiency virus and is used in the treatment and research of HIV/AIDS.

Afoxolaner is a potent isoxazoline ectoparasiticide indicated for the treatment and prevention of flea and tick infestations (Ixodes, Rhipicephalus, Dermacentor) in canines. Its mechanism of action involves the selective antagonism of GABA- and glutamate-gated chloride channels in the invertebrate nervous system, inducing hyperexcitation and fatal paralysis. Characterized by rapid systemic absorption and an extended elimination half-life, Afoxolaner supports a once-monthly oral dosing regimen and is frequently formulated with milbemycin oxime to provide broad-spectrum protection against both ectoparasites and endoparasites.

Afuresertib is an oral AKT kinase inhibitor that inhibits tumor cell growth by blocking the PI3K-AKT signaling pathway. It is primarily used in targeted therapy research for multiple myeloma and various solid tumors.

Apalutamide is a prescription medication used to treat non-metastatic, castration-resistant prostate cancer. It works by blocking the hormones that fuel cancer growth, helping to delay the spread of cancer and improve outcomes.

Articaine is a modern, fast-acting local anesthetic commonly used in dental procedures to provide safe and effective pain control.

Baloxavir marboxil is an oral antiviral medication used for the treatment of acute, uncomplicated influenza (flu) in adults and children.

Bemnifosbuvir is an investigational drug under development, primarily investigated for the treatment of hepatitis C virus (HCV) infection. It belongs to the class of NS5B polymerase inhibitors, which work by inhibiting viral replication, thereby aiding in the control and management of the infection.

Berzosertib is an investigational small-molecule drug that selectively inhibits the ATR kinase, a key protein in the DNA damage response pathway. Clinical trials have evaluated its potential, often in combination with chemotherapy or other targeted agents, for treating various advanced solid tumors including ovarian neoplasms, non-small cell lung cancer, and head and neck cancers.

Bilastine is a prescription medication belonging to a new generation of antihistamines, used for the effective relief of symptoms associated with allergic conditions such as allergic rhinitis (hay fever) and urticaria (hives).

Brinzolamide is a medication used in the treatment of glaucoma and ocular hypertension. As a carbonic anhydrase inhibitor, it primarily works by reducing the production of intraocular fluid (aqueous humor), thereby lowering intraocular pressure and helping to prevent vision loss associated with glaucoma.