Afuresertib
CandidateCAS: 1047644-62-1
Sample Stock:
Afuresertib is an oral AKT kinase inhibitor that inhibits tumor cell growth by blocking the PI3K-AKT signaling pathway. It is primarily used in targeted therapy research for multiple myeloma and various solid tumors.
Related Information
Purity:99%+
Registration:GMP/DMF
Biological Profile
Biological Targets
AKT2·AKT3·AKT1
Associated Conditions
ovarian cancer·prostate cancer·multiple myeloma·neoplasm·cancer·
Key Intermediates
9 Items| Structure | Name | CAS No. | Sample Stock | MDL No. | Details |
|---|---|---|---|---|---|
 | Methyl 4-bromo-5-chlorothiophene-2-carboxylate | 1047630-72-7 | MFCD28359275 | ||
 | Methyl 5-chloro-4-(1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxylate | 1047630-52-3 | MFCD28359276 | ||
 | 5-Chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxylic acid | 1047630-61-4 | MFCD28385904 | ||
![5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-N-{(1S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-[(3-fluorophenyl)methyl]ethyl}-2-thiophenecarboxamide structure](https://static.dempochem.com/structures-bw/69b827bb016d9ddc551776a8.svg) | 5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-N-{(1S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-[(3-fluorophenyl)methyl]ethyl}-2-thiophenecarboxamide | 1047645-80-6 | - | ||
 | (S)-tert-Butyl (1-(1,3-dioxoisoindolin-2-yl)-3-(3-fluorophenyl)propan-2-yl)carbamate | 1201923-48-9 | MFCD28359281 | ||
 | 1-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole | 847818-74-0 | MFCD05861380 | ||
 | (S)-2-(2-amino-3-(3-fluorophenyl)propyl)isoindoline-1,3-dione | 943325-38-0 | MFCD28359295 | ||
 | N-((1,1-Dimethylethoxy)carbonyl)-3-fluoro-L-phenylalanine | 114873-01-7 | MFCD00672522, MFCD05865250 | ||
 | (S)-tert-Butyl (1-(3-fluorophenyl)-3-hydroxypropan-2-yl)carbamate | 944470-56-8 | MFCD28359279 |