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Chemical structure of CAS 180300-43-0

Tas-106

In Stock•Starting at $87 for 1 mg
CAS No.180300-43-0
MDL No.MFCD00942308
MFC11H13N3O5
MW267.24
InChI KeyJFIWEPHGRUDAJN-DYUFWOLASA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mgTo Be Confirmed$87In Stock
5 mgTo Be Confirmed$210In Stock
10 mgTo Be Confirmed$360In Stock
25 mgTo Be Confirmed$774In Stock
50 mgTo Be Confirmed$1081In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

3'-C-Ethynylcytidine is a pyrimidine nucleoside.

CAS No.180300-43-0
Product NameTas-106

Biological Targets

POLR1A·POLR2A·POLR3A

Associated Conditions

cancer·head and neck malignant neoplasia
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Determination of 3'-C-ethynylcytidine in human plasma and urine by liquid chromatographic-electrospray ionization tandem mass spectrometry.

Journal of pharmaceutical and biomedical analysis • Vol. 31, Issue 1 • 2003
PMID: 12560048DOI: 10.1016/s0731-7085(02)00607-6

Synthesis of the cyclic and acyclic acetal derivatives of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine, a potent antitumor nucleoside. Design of prodrugs to be selectively activated in tumor tissues via the bio-reduction-hydrolysis mechanism.

Bioorganic & medicinal chemistry • Vol. 11, Issue 11 • 2003
PMID: 12735992DOI: 10.1016/s0968-0896(03)00104-4

Cellular and biochemical mechanisms of the resistance of human cancer cells to a new anticancer ribo-nucleoside, TAS-106.

Japanese journal of cancer research : Gann • Vol. 93, Issue 4 • 2002
PMID: 11985795PMC: PMC5927010DOI: 10.1111/j.1349-7006.2002.tb01276.x

Sensitivity of human cancer cells to the new anticancer ribo-nucleoside TAS-106 is correlated with expression of uridine-cytidine kinase 2.

Japanese journal of cancer research : Gann • Vol. 93, Issue 7 • 2002
PMID: 12149149PMC: PMC5927072DOI: 10.1111/j.1349-7006.2002.tb01325.x

Documentation

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