Non-catalog & advanced intermediates
Custom building blocks, pharmaceutical intermediates, and route-specific compounds prepared against defined specifications.
Custom Synthesis Service
Route assessment, non-catalog synthesis, process development, and scale-up support from research quantities through kilogram-scale supply. Each project is reviewed against the target structure, specification, analytical package, and delivery requirement.
PROJECT FOCUSTarget structureSpecificationDelivery requirement
Built around the target.
Chiral & structurally complex targets
Stereochemically defined compounds, functionalized heterocycles, and targets requiring selective or multi-step synthetic routes.
Fluorinated & specialty compounds
Fluorinated fragments, protected intermediates, and difficult-to-source structures for research and development programs.
Reference & impurity compounds
Specified reference materials, process-related impurities, and defined compounds for analytical or development work.
A defined route from technical brief to material.
Small-molecule custom synthesis connects target definition, route development, process scale-up, and material delivery in one coordinated path.
Request a custom synthesis assessment.
Custom Synthesis FAQ
A target identity or structure, requested quantity, purity or other key specifications, and the required delivery window are sufficient for an initial assessment. Literature, patents, route references, or structure files can be provided when available.
Yes. DempoChem can begin a technical review from a CAS number, SMILES, structure description, publication, patent, or synthesis reference. Additional structure files can be exchanged with the project team after the initial request.
Projects can be assessed from milligram and gram quantities through larger follow-on and kilogram-scale supply. Practical scale is determined by the route, starting-material access, target specification, and project requirements.
Analytical requirements are matched to the target and project purpose, with specifications defined before execution rather than added as a generic checklist after synthesis. Depending on scope, release packages typically include a Certificate of Analysis with identity and purity testing (HPLC/UPLC, LC-MS, NMR), stereochemical analysis (chiral HPLC) where required, defined specification reviews, and route or process documentation when included.
Lead time is assessed from molecular complexity, route availability, starting-material access, number of steps, requested quantity, specification, analytical requirements, and delivery expectations. An estimated schedule is provided with the proposal.