Stereochemical Precision

Chiral Synthesis

We treat chirality as a design constraint, building asymmetric routes that stand up to scale-up, validation, and commercial scrutiny.

Laboratory glassware capturing the precision required for chiral synthesis workflows.

Route development

From discovery briefing to launch stock

Route scouting starts with the business goal in mind: deliver the right enantiomer with predictable cost-of-goods. We combine computational screening with lab experience to prioritise catalytic pathways before touching kilo quantities.

  • Parallel screening for ligands, solvents, and bases to lock in optimal selectivity early.
  • Integrated analytical support with chiral HPLC, UPC2, and qNMR running beside the chemists.
  • Tech-transfer packages that document catalyst life, impurity fate, and crystallisation behaviour.

Methods

How we approach chiral programs

Asymmetric catalysis

Homogeneous and heterogeneous catalysts deliver high ee with efficient recycle strategies for metals and ligands.

Smart resolutions

Classical resolution is re-imagined with custom resolving agents and continuous mother-liquor recovery.

Biocatalytic routes

When enzymes win, our fermentation colleagues deliver tailored biocatalysts with predictable supply.

Instrumentation we lean on. Analytical control anchors every chiral decision. Our labs are equipped to follow enantiomeric excess minute-by-minute.

Contact us

Discuss Your Project

Tell us what you need to make, source, or scale. Our team will route your request to the right specialist.

Product sourcing
Custom synthesis
Scale-up support
info@dempochem.com
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