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Chemical structure of CAS 920014-72-8

Setmelanotide

CAS No.920014-72-8
MDL No.N/A
MFC49H68N18O9S2
MW1117.30
InChI KeyHDHDTKMUACZDAA-PHNIDTBTSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.920014-72-8
Product NameSetmelanotide

Biological Targets

MC4R

Associated Conditions

Prader-Willi syndrome·obesity·Renal insufficiency·morbid obesity·Bardet-Biedl syndrome
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials.

The lancet. Diabetes & endocrinology • Vol. 8, Issue 12 • 2020
PMID: 33137293DOI: 10.1016/S2213-8587(20)30364-8

Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.

The New England journal of medicine • Vol. 375, Issue 3 • 2016
PMID: 27468060DOI: 10.1056/NEJMoa1512693

RM-493, a melanocortin-4 receptor (MC4R) agonist, increases resting energy expenditure in obese individuals.

The Journal of clinical endocrinology and metabolism • Vol. 100, Issue 4 • 2015
PMID: 25675384PMC: PMC4399297DOI: 10.1210/jc.2014-4024

The melanocortin-4 receptor as target for obesity treatment: a systematic review of emerging pharmacological therapeutic options.

International journal of obesity (2005) • Vol. 38, Issue 2 • 2014
PMID: 23774329DOI: 10.1038/ijo.2013.80

Documentation

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