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Chemical structure of CAS 865363-93-5

4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine

In Stock•Starting at $73 for 5 mg•Purity ≥ 98%
CAS No.865363-93-5
MDL No.N/A
MFC12H12FN5O3
MW293.25
InChI KeyIKKXOSBHLYMWAE-QRPMWFLTSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
5 mg98%$73In Stock
10 mg98%$120In Stock
25 mg98%$222In Stock
50 mg98%$374In Stock
100 mg98%$634In Stock
250 mg98%$1265In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.865363-93-5
Product Name4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine

Associated Conditions

HIV infection·HIV-1 infection·viral disease
* The information provided here is compiled from public sources and is for reference only.

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Studies related to this compound and its mechanism of action

Hypersusceptibility mechanism of Tenofovir-resistant HIV to EFdA.

Retrovirology • Vol. 10 • 2013
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Response of simian immunodeficiency virus to the novel nucleoside reverse transcriptase inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine in vitro and in vivo.

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Development of modified nucleosides that have supremely high anti-HIV activity and low toxicity and prevent the emergence of resistant HIV mutants.

Proceedings of the Japan Academy. Series B, Physical and biological sciences • Vol. 87, Issue 3 • 2011
PMID: 21422739PMC: PMC3066546DOI: 10.2183/pjab.87.53

Potent activity of a nucleoside reverse transcriptase inhibitor, 4'-ethynyl-2-fluoro-2'-deoxyadenosine, against human immunodeficiency virus type 1 infection in a model using human peripheral blood mononuclear cell-transplanted NOD/SCID Janus kinase 3 knockout mice.

Antimicrobial agents and chemotherapy • Vol. 53, Issue 9 • 2009
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Documentation

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