| CAS No. | 625115-52-8 |
|---|---|
| MDL No. | MFCD22741546 |
| MF | C19H17FN8O2 |
| MW | 408.40 |
| InChI Key | FTQHGWIXJSSWOY-UHFFFAOYSA-N |
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| 100 mg | 98% | $43 | In Stock | |
| 250 mg | 98% | $86 | In Stock | |
| 1 g | 98% | $224 | In Stock | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Nelociguat is a pyrazolopyridine, specifically 1H-pyrazolo[3,4-b]pyridine, substituted with a 2-fluorobenzyl group at position 1 and a 4,6-diamino-5-[(methoxycarbonyl)amino]pyrimidin-2-yl group at position 3. It is an active metabolite of riociguat and a soluble guanylate cyclase stimulator developed by Bayer for the treatment of erectile dysfunction and heart failure. It functions as a soluble guanylate cyclase activator, antihypertensive agent, drug metabolite, and vasodilator. It belongs to the classes of monofluorobenzenes, carbamate esters, and aminopyrimidines.
| CAS No. | 625115-52-8 |
|---|---|
| Product Name | Nelociguat |
| Heavy Atom Count | 30 | Rotatable Bond Count | 4 |
| Atom Stereo Count | 0 | Bond Stereo Count | 0 |
| HBA | 9 | HBD | 3 |
| TPSA | 146.860 Ų | Charge | 0 |
| Exact Mass | 408.14585 | Complexity | 1233.50 |
| pKa | 7.130 | XLogP | 2.418 |
