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Chemical structure of CAS 610798-31-7

Icotinib

CAS No.610798-31-7
MDL No.MFCD22124501
MFC22H21N3O4
MW391.40
InChI KeyQQLKULDARVNMAL-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.610798-31-7
Product NameIcotinib

Biological Targets

EGFR

Associated Conditions

lung cancer·neoplasm·breast cancer·non-small cell lung carcinoma·pancreatic carcinoma·
* The information provided here is compiled from public sources and is for reference only.

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Studies related to this compound and its mechanism of action

Nrf2 but not autophagy inhibition is associated with the survival of wild-type epidermal growth factor receptor non-small cell lung cancer cells.

Toxicology and applied pharmacology • Vol. 310 • 2016
PMID: 27639429PMC: PMC5470646DOI: 10.1016/j.taap.2016.09.010

Investigation on the protein-binding properties of icotinib by spectroscopic and molecular modeling method.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy • Vol. 161 • 2016
PMID: 26963729DOI: 10.1016/j.saa.2016.02.014

Icotinib, a selective EGF receptor tyrosine kinase inhibitor, for the treatment of non-small-cell lung cancer.

Future oncology (London, England) • Vol. 11, Issue 3 • 2015
PMID: 25675121DOI: 10.2217/fon.14.249

Icotinib: activity and clinical application in Chinese patients with lung cancer.

Expert opinion on pharmacotherapy • Vol. 15, Issue 5 • 2014
PMID: 24588695DOI: 10.1517/14656566.2014.890183

Documentation

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