SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis.
Antimicrobial agents and chemotherapy • Vol. 56, Issue 4 • 2012
Design, synthesis, and biological evaluation of novel fluorinated ethanolamines.
Chemistry (Weinheim an der Bergstrasse, Germany) • Vol. 17, Issue 52 • 2011
Novel linear diamine disubstituted polycyclic 'cage' derivatives as potential antimycobacterial candidates.
Chemical biology & drug design • Vol. 78, Issue 6 • 2011
In vitro interactions between new antitubercular drug candidates SQ109 and TMC207.
Antimicrobial agents and chemotherapy • Vol. 54, Issue 7 • 2010