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Chemical structure of CAS 378-44-9

Betamethasone

CAS No.378-44-9
MDL No.MFCD00062929
MFC22H29FO5
MW392.50
InChI KeyUREBDLICKHMUKA-DVTGEIKXSA-N

Pricing & Availability

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Product Information

Betamethasone is a glucocorticoid steroid characterized by 20-oxo, 21-hydroxy, 17α-hydroxy, fluorinated, 11β-hydroxy, 3-oxo-Δ(1),Δ(4)-, primary α-hydroxy ketone, and tertiary α-hydroxy ketone functionalities. It functions as an anti-inflammatory, anti-asthmatic, and immunosuppressive agent, derived from a pregnane hydride.

CAS No.378-44-9
Product NameBetamethasone

Biological Targets

NR3C1

Associated Conditions

allergic disease·respiratory distress syndrome in premature infants·newborn respiratory distress syndrome·Sciatica·oral lichen planus·
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Effect of antenatal betamethasone treatment on microtubule-associated proteins MAP1B and MAP2 in fetal sheep.

The Journal of physiology • Vol. 530, Issue Pt 3 • 2001
PMID: 11158279PMC: PMC2278421DOI: 10.1111/j.1469-7793.2001.0497k.x

Repeated fetal betamethasone treatment and birth weight and head circumference.

Obstetrics and gynecology • Vol. 97, Issue 2 • 2001
PMID: 11165599DOI: 10.1016/s0029-7844(00)01110-8

Repeated courses of antenatal corticosteroids.

Obstetrics and gynecology • Vol. 97, Issue 2 • 2001
PMID: 11165602DOI: 10.1016/s0029-7844(00)01153-4

Antenatal betamethasone treatment reduces synaptophysin immunoreactivity in presynaptic terminals in the fetal sheep brain.

Neuroscience letters • Vol. 297, Issue 3 • 2001
PMID: 11137749DOI: 10.1016/s0304-3940(00)01605-0

Documentation

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