Alvocidib
| CAS No. | 146426-40-6 |
|---|---|
| MDL No. | MFCD20501884 |
| MF | C21H20ClNO5 |
| MW | 401.80 |
| InChI Key | BIIVYFLTOXDAOV-YVEFUNNKSA-N |
Pricing & Availability
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| - | - | On Request | On Request | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Product Information
Alvocidib is a synthetic dihydroxyflavone, specifically 5,7-dihydroxyflavone, substituted with a 3-hydroxy-1-methylpiperidin-4-yl group at position 8 and a chlorine at the 2' position (the (-)-3S,4R stereoisomer). It is a CDK9 inhibitor studied for acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation. It functions as an antineoplastic agent, EC 2.7.11.22 inhibitor, antirheumatic drug, and apoptosis inducer. It is classified as a dihydroxyflavone, hydroxypiperidine, monochlorobenzene, and tertiary amino compound, and is the conjugate base of alvocidib(1+).
| CAS No. | 146426-40-6 |
|---|---|
| Product Name | Alvocidib |
Biological Targets
CDK1·CDK2·CDK4·CDK6·CDK7·
Associated Conditions
Mantle cell lymphoma·follicular lymphoma·acute myeloid leukemia·neoplasm·prolymphocytic leukemia·
* The information provided here is compiled from public sources and is for reference only.
