Suramin
In Stock•Starting at $41 for 1 mg•Purity ≥ 98%
| CAS No. | 145-63-1 |
|---|---|
| MDL No. | N/A |
| MF | C51H40N6O23S6 |
| MW | 1297.30 |
| InChI Key | FIAFUQMPZJWCLV-UHFFFAOYSA-N |
Pricing & Availability
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| 1 mg | 98% | $41 | In Stock | |
| 5 mg | 98% | $104 | In Stock | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Product Information
Suramin is a phenylurea in which each amino group of urea is substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. It acts as an activator of rabbit skeletal muscle RyR1 and sheep cardiac RyR2 ryanodine receptor channels. Used for over 100 years in treating human African trypanosomiasis, it functions as a ryanodine receptor agonist, GABA-gated chloride channel antagonist, GABA antagonist, apoptosis inhibitor, antineoplastic agent, angiogenesis inhibitor, purinergic P2 receptor antagonist, protein kinase C inhibitor, antinematodal drug, and trypanocidal agent. It belongs to phenylureas, secondary carboxamides, and naphthalenesulfonic acids, and is functionally related to naphthalene-1,3,5-trisulfonic acid. It is the conjugate acid of suramin(6-).
| CAS No. | 145-63-1 |
|---|---|
| Product Name | Suramin |
Biological Targets
FGF1
Associated Conditions
prostate cancer·renal cell carcinoma·breast cancer·trypanosomiasis·adrenal cortex carcinoma·
* The information provided here is compiled from public sources and is for reference only.