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Chemical structure of CAS 129260-79-3

Loteprednol

CAS No.129260-79-3
MDL No.N/A
MFC21H27ClO5
MW394.90
InChI KeyYPZVAYHNBBHPTO-MXRBDKCISA-N
CUSTOM SYNTHESIS

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Product Information

Loteprednol is an 11beta-hydroxy, 17alpha-hydroxy steroid, an androstanoid, an organochlorine compound, a steroid acid ester, and a 3-oxo-Delta(1),Delta(4)-steroid. It functions as an antilipemic drug.

CAS No.129260-79-3
Product NameLoteprednol
Heavy Atom Count27Rotatable Bond Count2
Atom Stereo Count7Bond Stereo Count0
HBA5HBD2
TPSA83.830 ŲCharge0
Exact Mass394.15470Complexity744.85
pKa11.175XLogP2.736

Related Articles

Studies related to this compound and its mechanism of action

Comparison of the safety and efficacy of loteprednol 0.5%/tobramycin 0.3% with dexamethasone 0.1%/tobramycin 0.3% in the treatment of blepharokeratoconjunctivitis.

Current medical research and opinion • Vol. 24, Issue 1 • 2008
PMID: 18062846DOI: 10.1185/030079908x253898

Can corticosteroids be beaten in future asthma therapy?

Die Pharmazie • Vol. 61, Issue 2 • 2006
PMID: 16526559

Comparison of ketorolac tromethamine, diclofenac sodium, and loteprednol etabonate in an animal model of ocular inflammation.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics • Vol. 22, Issue 3 • 2006
PMID: 16808675DOI: 10.1089/jop.2006.22.155

Long-term safety of loteprednol etabonate 0.2% in the treatment of seasonal and perennial allergic conjunctivitis.

Eye & contact lens • Vol. 30, Issue 1 • 2004
PMID: 14722462DOI: 10.1097/01.ICL.0000092071.82938.46

Documentation

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