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Chemical structure of CAS 104987-11-3

Tacrolimus

In Stock•Starting at $22 for 50 mg•Purity ≥ 98%
CAS No.104987-11-3
MDL No.MFCD11045918
MFC44H69NO12
MW804.00
InChI KeyQJJXYPPXXYFBGM-LFZNUXCKSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
50 mg98%$22In Stock
100 mg98%$31In Stock
250 mg98%$60In Stock
1 g98%$144In Stock
5 g98%$473In Stock
10 g98%$850In Stock
25 g98%$1620In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Tacrolimus (anhydrous) is a macrolide lactam with a 23-membered lactone ring, originally isolated from the fermentation broth of a Japanese soil sample containing *Streptomyces tsukubaensis*. It functions as an immunosuppressive agent and bacterial metabolite.

CAS No.104987-11-3
Product NameTacrolimus

Biological Targets

FKBP1A

Associated Conditions

medication adherence behavior·acute kidney tubular necrosis·chronic kidney disease·sickle cell disease·Juvenile Myelomonocytic Leukemia·
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

The Immunosuppressant Macrolide Tacrolimus Activates Cold-Sensing TRPM8 Channels.

The Journal of neuroscience : the official journal of the Society for Neuroscience • Vol. 39, Issue 6 • 2019
PMID: 30545944PMC: PMC6363935DOI: 10.1523/JNEUROSCI.1726-18.2018

Metabolism of tacrolimus (FK506) and recent topics in clinical pharmacokinetics.

Drug metabolism and pharmacokinetics • Vol. 22, Issue 5 • 2007
PMID: 17965516DOI: 10.2133/dmpk.22.328

Delayed effect of grapefruit juice on pharmacokinetics and pharmacodynamics of tacrolimus in a living-donor liver transplant recipient.

Drug metabolism and pharmacokinetics • Vol. 21, Issue 2 • 2006
PMID: 16702731DOI: 10.2133/dmpk.21.122

Sourcing a chemical succession for cyclosporin from parasites and human pathogens.

Drug discovery today • Vol. 10, Issue 10 • 2005
PMID: 15896681DOI: 10.1016/S1359-6446(05)03395-7

Documentation

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