LMNG

Lauryl Maltose Neopentyl Glycol

CAS 1257852-96-2 · View compound details

Packs & prices

LMNG packaging and prices in USD and EUR
Pack size	Price (USD / EUR)	Enquire
1 gDC-R0001-1G	$122 / €109
5 gDC-R0001-5G	$421 / €376
25 gDC-R0001-25G	$1,684 / €1,504

1 gDC-R0001-1G
$122 / €109
5 gDC-R0001-5G
$421 / €376
25 gDC-R0001-25G
$1,684 / €1,504

Notice: Prices are per pack in USD / EUR. Enquire to confirm availability, lead time, shipping costs and applicable taxes. Contact us for bulk or recurring supply.

Product overview

LMNG has a neopentyl glycol core with a double-head, double-tail architecture. Its mild solubilization profile supports work with challenging membrane proteins, including GPCRs and ion channels. It can be used with other detergents or a cholesterol-derived additive such as CHS during extraction, affinity purification and size-exclusion chromatography.

Product specifications

CAS number: 1257852-96-2
Molecular formula: C₄₇H₈₈O₂₂
Molecular weight: 1005.19 g/mol
Chemical name: 2,2-Didecylpropane-1,3-diylbis[4-O-α-D-glucopyranosyl-β-D-glucopyranoside]
Appearance: White solid
Purity specification: ≥ 98.0%
Critical micelle concentration (water): Approximately 0.01 mM (0.001%)
pH: 5–8 (1% solution in water)
Conductance: < 100 μS (5% solution in water)
Water solubility: ≥ 5% at 20 °C
Storage: Powder: −20 °C, up to 3 years. In solvent: −80 °C, up to 1 year, according to the technical sheet.

Identity and analytical characterization

Representative analytical records. The chromatogram belongs to the sample identified below; its peak-area percentage is distinct from the product purity specification.

LMNG proton NMR spectrum — **¹H NMR spectrum**Representative ¹H NMR record for LMNG.

LMNG HPLC and ELSD analytical report in English — **HPLC / ELSD analytical record**Sample LM-0527 · UV / ELSD · 2 μL injection.

HPLC peak integration · LM-0527

HPLC peak integration · LM-0527
Peak	RT (min)	Area	Height	Height (%)	Area (%)
1	3.449	1,126	147	0.027	0.026
2	4.258	4,293,344	542,607	99.914	99.953
3	4.758	883	322	0.059	0.021
Total	—	4,295,354	543,076	100.000	100.000

LMNG / CHS membrane protein validation

Application data for LMNG and CHS used together. These results describe the tested receptor preparations and do not represent a universal outcome for every membrane protein.

SEC-HPLC chromatograms of hNTSR1 and A₂AR — **SEC-HPLC of purified hNTSR1 and A₂AR**Predominant main peaks with minor aggregate peaks.

SDS-PAGE gel of purified hNTSR1 and A₂AR — **SDS-PAGE of purified GPCRs**hNTSR1 and A₂AR bands at the expected molecular weights.

Cryo-EM maps of A₂AR–Gs and GCGR–Gs — **Cryo-EM structure examples**LMNG / CHS preparations: A₂AR–Gs, 2.86 Å; GCGR–Gs, 3.69 Å.

Handling & use

LMNG and CHS are supplied separately. Select and optimize their working concentrations for the target protein and purification workflow.

Representative analytical records are not a batch-specific certificate of analysis.