N-[(2S)-1-[4-[(2S)-2-[(2,4-dichlorophenyl)sulfonylamino]-3-hydroxypropanoyl]piperazin-1-yl]-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide

GSK1016790A is a tertiary carboxamide and N-acylpiperazine, where one amino group is condensed with the carboxy group of N-[(2,4-dichlorophenyl)sulfonyl]-L-serine, and the other with the carboxy group of N-(1-benzothiophen-2-ylcarbonyl)-L-leucine. It is a cell-permeable, potent, and selective agonist of the TRPV4 channel. It belongs to the classes of 1-benzothiophenes, sulfonamides, dichlorobenzenes, tertiary carboxamides, and aromatic primary alcohols.