HomeProductsBioactive CompoundsImmunology & InflammationHistamine ReceptorCAS 935840-31-6
Chemical structure of CAS 935840-31-6

N-ethyl-3-fluoro-3-(3-fluoro-4-(pyrrolidinylmethyl)phenyl)cyclobutanecarboxamide

In Stock•Starting at $830 for 5 mg•Purity ≥ 98%
CAS No.935840-31-6
MDL No.N/A
MFC18H24F2N2O
MW322.40
InChI KeySXMBKHYDZOCBMT-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
5 mg98%$830In Stock
25 mg98%$1244In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.935840-31-6
Product NameN-ethyl-3-fluoro-3-(3-fluoro-4-(pyrrolidinylmethyl)phenyl)cyclobutanecarboxamide

Biological Targets

HRH3

Associated Conditions

allergic rhinitis·attention deficit hyperactivity disorder·Alzheimer disease·schizophrenia·Tourette syndrome
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

The effects of an H3 receptor antagonist (PF-03654746) with fexofenadine on reducing allergic rhinitis symptoms.

The Journal of allergy and clinical immunology • Vol. 129, Issue 2 • 2012
PMID: 22196768DOI: 10.1016/j.jaci.2011.11.026

Discovery of two clinical histamine H(3) receptor antagonists: trans-N-ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidinylmethyl)phenyl]cyclobutanecarboxamide (PF-03654746) and trans-3-fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]-N-(2-methylpropyl)cyclobutanecarboxamide (PF-03654764).

Journal of medicinal chemistry • Vol. 54, Issue 21 • 2011
PMID: 21928839DOI: 10.1021/jm200939b

Discovery of histamine H3 antagonists for the treatment of cognitive disorders and Alzheimer's disease.

The Journal of pharmacology and experimental therapeutics • Vol. 336, Issue 1 • 2011
PMID: 20864505DOI: 10.1124/jpet.110.166876

Documentation

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