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Chemical structure of CAS 88847-89-6

8-Hydroxy-2'-Deoxyguanosine

In Stock•Starting at $15 for 100 mg•Purity ≥ 96%
CAS No.88847-89-6
MDL No.N/A
MFC10H13N5O5
MW283.24
InChI KeyHCAJQHYUCKICQH-VPENINKCSA-N
CUSTOM SYNTHESIS

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
100 mg96%$15In Stock
250 mg96%$23In Stock
1 g96%$50In Stock
5 g96%$207In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

8-Hydroxy-2'-deoxyguanosine is a guanosine derivative with a hydroxy group at the purine 8-position. It serves as a biomarker for oxidative DNA damage.

CAS No.88847-89-6
Product Name8-Hydroxy-2'-Deoxyguanosine
Heavy Atom Count20Rotatable Bond Count2
Atom Stereo Count3Bond Stereo Count0
HBA8HBD5
TPSA159.250 ŲCharge0
Exact Mass283.09167Complexity761.46
pKa7.130XLogP-2.364

Related Articles

Studies related to this compound and its mechanism of action

2'-deoxyguanosine oxidation is associated with decrease in the DNA-binding activity of the transcription factor Sp1 in liver and kidney from diabetic and insulin-resistant rats.

Free radical biology & medicine • Vol. 30, Issue 1 • 2001
PMID: 11134901DOI: 10.1016/s0891-5849(00)00451-2

Protective effect of green tea extract on ischemia/reperfusion-induced brain injury in Mongolian gerbils.

Brain research • Vol. 888, Issue 1 • 2001
PMID: 11146047DOI: 10.1016/s0006-8993(00)02935-8

Protective effect of resveratrol on oxidative damage in male and female stroke-prone spontaneously hypertensive rats.

Clinical and experimental pharmacology & physiology • Vol. 28, Issue 1-2 • 2001
PMID: 11153537DOI: 10.1046/j.1440-1681.2001.03415.x

Increased oxidative DNA damage in mammary tumor cells by continuous epidermal growth factor stimulation.

Journal of the National Cancer Institute • Vol. 93, Issue 3 • 2001
PMID: 11158190DOI: 10.1093/jnci/93.3.214

Documentation

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