The discovery of PLK4 inhibitors: (E)-3-((1H-Indazol-6-yl)methylene)indolin-2-ones as novel antiproliferative agents.
Journal of medicinal chemistry • Vol. 56, Issue 15 • 2013
Discovery of a highly potent, orally active mitosis/angiogenesis inhibitor r1530 for the treatment of solid tumors.
ACS medicinal chemistry letters • Vol. 4, Issue 2 • 2013
Preclinical evaluation of the novel multi-targeted agent R1530.
Cancer chemotherapy and pharmacology • Vol. 68, Issue 6 • 2011
Small-molecule inducer of cancer cell polyploidy promotes apoptosis or senescence: Implications for therapy.
Cell cycle (Georgetown, Tex.) • Vol. 9, Issue 16 • 2010