Product Information

CAS No.	882531-87-5
Product Name	R-1530

Biological Targets

FGFR1·FGFR2·PDGFRB·AURKA·PLK4·

Associated Conditions

neoplasm

* The information provided here is compiled from public sources and is for reference only.

Studies related to this compound and its mechanism of action

The discovery of PLK4 inhibitors: (E)-3-((1H-Indazol-6-yl)methylene)indolin-2-ones as novel antiproliferative agents.

Journal of medicinal chemistry • Vol. 56, Issue 15 • 2013

PMID: 23829549 DOI: 10.1021/jm400380m

Discovery of a highly potent, orally active mitosis/angiogenesis inhibitor r1530 for the treatment of solid tumors.

ACS medicinal chemistry letters • Vol. 4, Issue 2 • 2013

PMID: 24900658 PMC: PMC4027509 DOI: 10.1021/ml300351e

Preclinical evaluation of the novel multi-targeted agent R1530.

Cancer chemotherapy and pharmacology • Vol. 68, Issue 6 • 2011

PMID: 21553286 DOI: 10.1007/s00280-011-1608-x

Small-molecule inducer of cancer cell polyploidy promotes apoptosis or senescence: Implications for therapy.

Cell cycle (Georgetown, Tex.) • Vol. 9, Issue 16 • 2010

PMID: 20814247 DOI: 10.4161/cc.9.16.12732

R-1530

CAS No.	882531-87-5
MDL No.	MFCD23704870
MF	C₁₈H₁₄ClFN₄O
MW	356.80
InChI Key	UOVCGJXDGOGOCZ-UHFFFAOYSA-N

CUSTOM SYNTHESIS PRECLINICAL SUPPORT

Pricing & Availability

Pack Size	Purity	Price	Availability	Action
-	-	On Request	On Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.	882531-87-5
Product Name	R-1530

Biological Targets

FGFR1·FGFR2·PDGFRB·AURKA·PLK4·

Associated Conditions

neoplasm

* The information provided here is compiled from public sources and is for reference only.

R-1530

Pricing & Availability

Product Information

Biological Profile

Safety Information

Properties

Biological Targets

Associated Conditions

R-1530

Pricing & Availability

Product Information

Biological Profile

Safety Information

Properties

Biological Targets

Associated Conditions

Documentation

R-1530

Pricing & Availability

Product Information

Biological Profile

Safety Information

Properties

Biological Targets

Associated Conditions

Related Articles

The discovery of PLK4 inhibitors: (E)-3-((1H-Indazol-6-yl)methylene)indolin-2-ones as novel antiproliferative agents.

Discovery of a highly potent, orally active mitosis/angiogenesis inhibitor r1530 for the treatment of solid tumors.

Preclinical evaluation of the novel multi-targeted agent R1530.

Small-molecule inducer of cancer cell polyploidy promotes apoptosis or senescence: Implications for therapy.

Similar Products

Tinengotinib

R-1530

Pricing & Availability

Product Information

Biological Profile

Safety Information

Properties

Biological Targets

Associated Conditions

Related Articles

The discovery of PLK4 inhibitors: (E)-3-((1H-Indazol-6-yl)methylene)indolin-2-ones as novel antiproliferative agents.

Discovery of a highly potent, orally active mitosis/angiogenesis inhibitor r1530 for the treatment of solid tumors.

Preclinical evaluation of the novel multi-targeted agent R1530.

Small-molecule inducer of cancer cell polyploidy promotes apoptosis or senescence: Implications for therapy.

Similar Products

Tinengotinib

Documentation