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Chemical structure of CAS 859853-30-8

Bms-690514

CAS No.859853-30-8
MDL No.MFCD18633295
MFC19H24N6O2
MW368.40
InChI KeyCSGQVNMSRKWUSH-IAGOWNOFSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.859853-30-8
Product NameBms-690514

Biological Targets

EGFR·ERBB2·ERBB4·FLT1·FLT4·

Associated Conditions

neoplasm·cancer·non-small cell lung carcinoma·breast cancer
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Mechanistic studies on a P450-mediated rearrangement of BMS-690514: conversion of a pyrrolotriazine to a hydroxypyridotriazine.

Chemical research in toxicology • Vol. 24, Issue 1 • 2011
PMID: 21080678DOI: 10.1021/tx100337s

Preclinical pharmacokinetics and in vitro metabolism of BMS-690514, a potent inhibitor of EGFR and VEGFR2.

Journal of pharmaceutical sciences • Vol. 99, Issue 8 • 2010
PMID: 20166197DOI: 10.1002/jps.22099

A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib.

Cancer research • Vol. 67, Issue 13 • 2007
PMID: 17616683DOI: 10.1158/0008-5472.CAN-07-0538

Documentation