Bedaquiline

Bedaquiline is a quinoline-based antimycobacterial drug used as its fumarate salt to treat pulmonary multi-drug resistant tuberculosis by inhibiting ATP synthase, an enzyme critical for mycobacterial replication. It functions as an antitubercular agent and ATP synthase inhibitor. It belongs to quinolines, naphthalenes, organobromine compounds, aromatic ethers, tertiary alcohols, and tertiary amines. It is the conjugate base of bedaquiline(2+).