Roxadustat
| CAS No. | 808118-40-3 |
|---|---|
| MDL No. | MFCD20040519 |
| MF | C19H16N2O5 |
| MW | 352.30 |
| InChI Key | YOZBGTLTNGAVFU-UHFFFAOYSA-N |
Pricing & Availability
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| - | - | On Request | On Request | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Product Information
Roxadustat is an N-acylglycine formed by the condensation of glycine's amino group with the carboxy group of 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid. It inhibits hypoxia-inducible factor prolyl hydroxylase (HIF-PH) and acts as an inhibitor of EC 1.14.11.2 (procollagen-proline dioxygenase) and EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase). It belongs to the classes of isoquinolines, aromatic ethers, and N-acylglycines.
| CAS No. | 808118-40-3 |
|---|---|
| Product Name | Roxadustat |
Biological Targets
EGLN2·P4HTM·EGLN1·EGLN3
Associated Conditions
myelodysplastic syndrome·anemia (phenotype)·kidney disease·ST Elevation Myocardial Infarction·chronic kidney disease
* The information provided here is compiled from public sources and is for reference only.
