Tanespimycin
In Stock•Starting at $30 for 1 mg•Purity ≥ 98%
| CAS No. | 75747-14-7 |
|---|---|
| MDL No. | MFCD04973892 |
| MF | C31H43N3O8 |
| MW | 585.70 |
| InChI Key | AYUNIORJHRXIBJ-TXHRRWQRSA-N |
Pricing & Availability
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| 1 mg | 98% | $30 | In Stock | |
| 5 mg | 98% | $35 | In Stock | |
| 10 mg | 98% | $66 | In Stock | |
| 25 mg | 98% | $111 | In Stock | |
| 50 mg | 98% | $165 | In Stock |
Product Information
Tanespimycin is a 19-membered macrocycle derived from geldanamycin, where the methoxy group on the benzoquinone moiety is replaced by an allylamino group. It is a potent Hsp90 inhibitor, less toxic than geldanamycin, and induces apoptosis with antitumour activity. It functions as an antineoplastic agent, Hsp90 inhibitor, and apoptosis inducer. Chemically, it is a secondary amino compound, ansamycin, carbamate ester, organic heterobicyclic compound, and member of 1,4-benzoquinones. It is functionally related to geldanamycin.
| CAS No. | 75747-14-7 |
|---|---|
| Product Name | Tanespimycin |
| Heavy Atom Count | 42 | Rotatable Bond Count | 6 |
| Atom Stereo Count | 6 | Bond Stereo Count | 3 |
| HBA | 9 | HBD | 4 |
| TPSA | 166.280 Ų | Charge | 0 |
| Exact Mass | 585.30502 | Complexity | 1212.43 |
| pKa | 7.130 | XLogP | 2.538 |
