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Chemical structure of CAS 70052-12-9

Eflornithine

In Stock•Starting at $28 for 10 mg•Purity ≥ 98%
CAS No.70052-12-9
MDL No.MFCD00221766
MFC6H12F2N2O2
MW182.17
InChI KeyVLCYCQAOQCDTCN-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
10 mg98%$28In Stock
25 mg99.84% ;$53In Stock
50 mg99.84% ;$75In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Eflornithine is a fluoroamino acid with a difluoromethyl group at position 2 of ornithine. It functions as a trypanocidal drug and is related to ornithine as an alpha-amino acid.

CAS No.70052-12-9
Product NameEflornithine

Biological Targets

ODC1

Associated Conditions

esophageal cancer·precancerous condition·colorectal neoplasm·neuroblastoma·colorectal cancer·
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts.

The Journal of biological chemistry • Vol. 276, Issue 2 • 2001
PMID: 10986279DOI: 10.1074/jbc.M003649200

Effects of chemopreventive and antitelomerase agents on the spontaneous immortalization of breast epithelial cells.

Journal of the National Cancer Institute • Vol. 93, Issue 1 • 2001
PMID: 11136840DOI: 10.1093/jnci/93.1.39

Alpha-difluoromethylornithine and polyamine levels in the human prostate: results of a phase IIa trial.

Journal of the National Cancer Institute • Vol. 93, Issue 1 • 2001
PMID: 11136843DOI: 10.1093/jnci/93.1.57

Uptake and mode of action of drugs used against sleeping sickness.

Biochemical pharmacology • Vol. 61, Issue 1 • 2001
PMID: 11137702DOI: 10.1016/s0006-2952(00)00477-9

Documentation

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