An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors.
Nature chemical biology • Vol. 2, Issue 4 • 2006
Functional integrity of the p53-mediated apoptotic pathway induced by the nongenotoxic agent nutlin-3 in B-cell chronic lymphocytic leukemia (B-CLL).
Blood • Vol. 107, Issue 10 • 2006
MDM2 antagonists activate p53 and synergize with genotoxic drugs in B-cell chronic lymphocytic leukemia cells.
Blood • Vol. 107, Issue 10 • 2006
Levels of HdmX expression dictate the sensitivity of normal and transformed cells to Nutlin-3.
Cancer research • Vol. 66, Issue 6 • 2006
