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Chemical structure of CAS 66376-36-1

Alendronic Acid

In Stock•Starting at $11 for 1 g•Purity ≥ 98%
CAS No.66376-36-1
MDL No.MFCD00868112
MFC4H13NO7P2
MW249.10
InChI KeyOGSPWJRAVKPPFI-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 g98%$11In Stock
5 g98%$34In Stock
25 g98%$123In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Alendronic acid is a 1,1-bis(phosphonic acid) derived from methanebis(phosphonic acid) with the two methylene hydrogens replaced by hydroxy and 3-aminopropyl groups. It functions as an EC 2.5.1.1 (dimethylallyltranstransferase) inhibitor and a bone density conservation agent. It is a primary amino compound and the conjugate acid of alendronate(1-).

CAS No.66376-36-1
Product NameAlendronic Acid

Biological Targets

FDPS

Associated Conditions

osteoarthritis·osteitis deformans·periodontitis·osteoporosis·bone disease·
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Phenotypic characteristics of human monocytes undergoing transendothelial migration.

Arthritis research • Vol. 3, Issue 2 • 2001
PMID: 11178120PMC: PMC17829DOI: 10.1186/ar150

Alendronate and naproxen are synergistic for development of gastric ulcers.

Archives of internal medicine • Vol. 161, Issue 1 • 2001
PMID: 11146706DOI: 10.1001/archinte.161.1.107

Effects of oral alendronate in elderly patients with osteoporosis and mild primary hyperparathyroidism.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research • Vol. 16, Issue 1 • 2001
PMID: 11149474DOI: 10.1359/jbmr.2001.16.1.113

Bisphosphonate therapy in fibrous dysplasia.

Clinical orthopaedics and related research, Issue 382 • 2001
PMID: 11154006DOI: 10.1097/00003086-200101000-00003

Documentation

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