The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology.
Immunology • Vol. 160, Issue 1 • 2020
E6201, a novel kinase inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-1 and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase-1: in vivo effects on cutaneous inflammatory responses by topical administration.
The Journal of pharmacology and experimental therapeutics • Vol. 335, Issue 1 • 2010
Discovery of anti-inflammatory clinical candidate E6201, inspired from resorcylic lactone LL-Z1640-2, III.
Bioorganic & medicinal chemistry letters • Vol. 20, Issue 10 • 2010
E6201 [(3S,4R,5Z,8S,9S,11E)-14-(ethylamino)-8, 9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione], a novel kinase inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-1 and MEK kinase-1: in vitro characterization of its anti-inflammatory and antihyperproliferative activities.
The Journal of pharmacology and experimental therapeutics • Vol. 331, Issue 2 • 2009