Product Information

CAS No.	577778-58-6
Product Name	Topiroxostat

Biological Targets

XDH

Associated Conditions

diabetic nephropathy·hyperuricemia

* The information provided here is compiled from public sources and is for reference only.

Studies related to this compound and its mechanism of action

Effects of topiroxostat on the serum urate levels and urinary albumin excretion in hyperuricemic stage 3 chronic kidney disease patients with or without gout.

Clinical and experimental nephrology • Vol. 18, Issue 6 • 2014

PMID: 24448692 PMC: PMC4271138 DOI: 10.1007/s10157-014-0935-8

QT/QTc study conducted in Japanese adult healthy subjects: a novel xanthine oxidase inhibitor topiroxostat was not associated with QT prolongation.

Journal of clinical pharmacology • Vol. 54, Issue 4 • 2014

PMID: 24214189 DOI: 10.1002/jcph.226

FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase.

The Journal of pharmacology and experimental therapeutics • Vol. 336, Issue 1 • 2011

PMID: 20952484 DOI: 10.1124/jpet.110.174540

Study on species differences in nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor.

Archives of toxicology • Vol. 85, Issue 5 • 2011

PMID: 20936465 DOI: 10.1007/s00204-010-0598-5

Topiroxostat

CAS No.	577778-58-6
MDL No.	MFCD17167057
MF	C₁₃H₈N₆
MW	248.24
InChI Key	UBVZQGOVTLIHLH-UHFFFAOYSA-N

CUSTOM SYNTHESIS PRECLINICAL SUPPORT

Pricing & Availability

Pack Size	Purity	Price	Availability	Action
-	-	On Request	On Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.	577778-58-6
Product Name	Topiroxostat

Biological Targets

XDH

Associated Conditions

diabetic nephropathy·hyperuricemia

* The information provided here is compiled from public sources and is for reference only.

Topiroxostat

Pricing & Availability

Product Information

Biological Profile

Properties

Biological Targets

Associated Conditions

Topiroxostat

Pricing & Availability

Product Information

Biological Profile

Properties

Biological Targets

Associated Conditions

Documentation

Topiroxostat

Pricing & Availability

Product Information

Biological Profile

Properties

Biological Targets

Associated Conditions

Related Articles

Effects of topiroxostat on the serum urate levels and urinary albumin excretion in hyperuricemic stage 3 chronic kidney disease patients with or without gout.

QT/QTc study conducted in Japanese adult healthy subjects: a novel xanthine oxidase inhibitor topiroxostat was not associated with QT prolongation.

FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase.

Study on species differences in nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor.

Topiroxostat

Pricing & Availability

Product Information

Biological Profile

Properties

Biological Targets

Associated Conditions

Related Articles

Effects of topiroxostat on the serum urate levels and urinary albumin excretion in hyperuricemic stage 3 chronic kidney disease patients with or without gout.

QT/QTc study conducted in Japanese adult healthy subjects: a novel xanthine oxidase inhibitor topiroxostat was not associated with QT prolongation.

FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase.

Study on species differences in nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor.

Documentation