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Chemical structure of CAS 557795-19-4

Sunitinib

CAS No.557795-19-4
MDL No.MFCD09260778
MFC22H27FN4O2
MW398.50
InChI KeyWINHZLLDWRZWRT-ATVHPVEESA-N

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Product Information

Sunitinib is a pyrrole and monocarboxylic acid amide with roles as an angiogenesis inhibitor, antineoplastic agent, EC 2.7.10.1 inhibitor, vascular endothelial growth factor receptor antagonist, immunomodulator, and neuroprotective agent. It is functionally related to 3-methyleneoxindole.

CAS No.557795-19-4
Product NameSunitinib
Health HazardHealth Hazard
Environmental HazardEnvironmental Hazard
Signal Word:Warning
HCode:H361-H373-H400-H410
PCode:P203-P260-P273-P280-P318-P319-P391-P405-P501

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Studies related to this compound and its mechanism of action

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Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.

Nature biotechnology • Vol. 29, Issue 11 • 2011
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Comprehensive analysis of kinase inhibitor selectivity.

Nature biotechnology • Vol. 29, Issue 11 • 2011
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Synthesis and structure-activity relationship of 6-arylureido-3-pyrrol-2-ylmethylideneindolin-2-one derivatives as potent receptor tyrosine kinase inhibitors.

Bioorganic & medicinal chemistry • Vol. 18, Issue 13 • 2010
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Documentation

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