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Chemical structure of CAS 5300-03-8

9-Cis-Retinoic Acid

In Stock•Starting at $20 for 1 mg•Purity ≥ 97%
CAS No.5300-03-8
MDL No.MFCD00270072
MFC20H28O2
MW300.40
InChI KeySHGAZHPCJJPHSC-ZVCIMWCZSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mg97%$20In Stock
5 mg97%$48In Stock
10 mg97%$62In Stock
100 mg97%$121In Stock
250 mg97%$203In Stock
1 g97%$531In Stock
5 g97%$2638In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

9-cis-Retinoic acid is a retinoic acid with 7E,9Z,11E,13E geometry for the exocyclic double bonds. It functions as an antineoplastic agent, retinoid X receptor agonist, metabolite, and keratolytic drug. It is the conjugate acid of 9-cis-retinoate.

CAS No.5300-03-8
Product Name9-Cis-Retinoic Acid

Biological Targets

RXRB·RARG·RXRG·RARB·RARA·

Associated Conditions

Eczematoid dermatitis·hand dermatosis·cutaneous lupus erythematosus·psoriasis·lichen planus·
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Both retinoic-acid-receptor- and retinoid-X-receptor-dependent signalling pathways mediate the induction of the brown-adipose-tissue-uncoupling-protein-1 gene by retinoids.

The Biochemical journal • Vol. 345 Pt 1, Issue Pt 1 • 2000
PMID: 10600643PMC: PMC1220734

Chelation of zinc amplifies induction of growth hormone mRNA levels in cultured rat pituitary tumor cells.

The Journal of nutrition • Vol. 130, Issue 2 • 2000
PMID: 10720163DOI: 10.1093/jn/130.2.158

Characterization of retinoic acid receptor-deficient keratinocytes.

The Journal of biological chemistry • Vol. 275, Issue 22 • 2000
PMID: 10748128DOI: 10.1074/jbc.M909382199

Induction of the fatty acid transport protein 1 and acyl-CoA synthase genes by dimer-selective rexinoids suggests that the peroxisome proliferator-activated receptor-retinoid X receptor heterodimer is their molecular target.

The Journal of biological chemistry • Vol. 275, Issue 17 • 2000
PMID: 10777552DOI: 10.1074/jbc.275.17.12612

Documentation

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