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Chemical structure of CAS 51568-18-4

4,6-Dioxoheptanoic acid

In Stock•Starting at $74 for 100 mg•Purity ≥ 97%
CAS No.51568-18-4
MDL No.MFCD00002797
MFC7H10O4
MW158.15
InChI KeyWYEPBHZLDUPIOD-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
100 mg98%$74In Stock
250 mg98%$128In Stock
1 g98%$255In Stock
5 g97%$1024In Stock
10 g97%$1636In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

4,6-Dioxoheptanoic acid is a dioxo monocarboxylic acid derived from heptanoic acid, with oxo groups replacing hydrogens at positions 4 and 6. It is an abnormal metabolite of the tyrosine metabolic pathway and serves as a marker for type 1 tyrosinaemia. It functions as a human metabolite and is a beta-diketone.

CAS No.51568-18-4
Product Name4,6-Dioxoheptanoic acid
IrritantIrritant
Signal Word:Warning
HCode:H315-H319-H335
PCode:P261-P264-P264+P265-P271-P280-P302+P352-P304+P340-P305+P351+P338-P319-P321-P332+P317-P337+P317-P362+P364-P403+P233-P405-P501

Related Articles

Studies related to this compound and its mechanism of action

Heme and heme biosynthesis intermediates induce heme oxygenase-1 and cytochrome P450 2A5, enzymes with putative sequential roles in heme and bilirubin metabolism: different requirement for transcription factor nuclear factor erythroid- derived 2-like 2.

Toxicological sciences : an official journal of the Society of Toxicology • Vol. 130, Issue 1 • 2012
PMID: 22859313DOI: 10.1093/toxsci/kfs237

Lon peptidase 1 (LONP1)-dependent breakdown of mitochondrial 5-aminolevulinic acid synthase protein by heme in human liver cells.

The Journal of biological chemistry • Vol. 286, Issue 30 • 2011
PMID: 21659532PMC: PMC3143606DOI: 10.1074/jbc.M110.215772

Nonactin biosynthesis: unexpected patterns of label incorporation from 4,6-dioxoheptanoate show evidence of a degradation pathway for levulinate through propionate in Streptomyces griseus.

Journal of natural products • Vol. 73, Issue 12 • 2010
PMID: 21138242DOI: 10.1021/np100421v

skn-1-Dependent and -independent regulation of aip-1 expression following metabolic stress in Caenorhabditis elegans.

Molecular and cellular biology • Vol. 30, Issue 11 • 2010
PMID: 20351174PMC: PMC2876512DOI: 10.1128/MCB.01340-09

Documentation

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