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Chemical structure of CAS 51322-75-9

Tizanidine

In Stock•Starting at $14 for 1 g•Purity ≥ 99%
CAS No.51322-75-9
MDL No.MFCD00865192
MFC9H8ClN5S
MW253.71
InChI KeyXFYDIVBRZNQMJC-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 g99%$14In Stock
5 g99%$40In Stock
25 g99%$129In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Tizanidine is a benzothiadiazole with a Delta(1)-imidazolin-2-ylamino group and a chloro group at C-4. It is an alpha2-adrenergic receptor agonist, functioning as an alpha-adrenergic agonist and muscle relaxant. It is a member of the imidazole class.

CAS No.51322-75-9
Product NameTizanidine

Biological Targets

ADRA2A·ADRA2C·ADRA2B

Associated Conditions

Spasticity·melanoma·brain injury·migraine without aura·Pain·
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Antagonistic effects of selective alpha1-adrenoceptor antagonists MDL73005EF and tamsulosin and partial agonists clonidine and tizanidine in rat thoracic aorta and rabbit iliac artery.

The Journal of pharmacy and pharmacology • Vol. 53, Issue 1 • 2001
PMID: 11206183DOI: 10.1211/0022357011775073

An open-label dose-titration study of the efficacy and tolerability of tizanidine hydrochloride tablets in the prophylaxis of chronic daily headache.

Headache • Vol. 41, Issue 4 • 2001
PMID: 11318882DOI: 10.1046/j.1526-4610.2001.111006357.x

Group II muscle afferents probably contribute to the medium latency soleus stretch reflex during walking in humans.

The Journal of physiology • Vol. 534, Issue Pt 3 • 2001
PMID: 11483721PMC: PMC2278750DOI: 10.1111/j.1469-7793.2001.00925.x

Open-label dose-titration safety and efficacy study of tizanidine hydrochloride in the treatment of spasticity associated with chronic stroke.

Stroke • Vol. 32, Issue 8 • 2001
PMID: 11486114DOI: 10.1161/01.str.32.8.1841

Documentation

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