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Chemical structure of CAS 50264-69-2

Lonidamine

In Stock•Starting at $46 for 100 mg•Purity ≥ 99%
CAS No.50264-69-2
MDL No.MFCD00866285
MFC15H10Cl2N2O2
MW321.20
InChI KeyWDRYRZXSPDWGEB-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
100 mg99%$46In Stock
250 mg99%$72In Stock
1 g99%$180In Stock
5 g99%$592In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Lonidamine is an indazole with substituents at positions 1 and 3: 2,4-dichlorobenzyl and a carboxy group, respectively. It functions as an antispermatogenic, antineoplastic, geroprotective agent, and inhibitor of EC 2.7.1.1 (hexokinase). It belongs to the classes of indazoles, dichlorobenzenes, and monocarboxylic acids.

CAS No.50264-69-2
Product NameLonidamine

Associated Conditions

benign prostatic hyperplasia·neoplasm
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Recent studies on lonidamine, the lead compound of the antispermatogenic indazol-carboxylic acids.

Contraception • Vol. 65, Issue 4 • 2002
PMID: 12020777DOI: 10.1016/s0010-7824(02)00289-5

Analysis of lonidamine in rat serum and testis by high performance liquid chromatography.

Biomedical chromatography : BMC • Vol. 15, Issue 1 • 2001
PMID: 11180293DOI: 10.1002/bmc.14

Paclitaxel, cisplatin and lonidamine in advanced ovarian cancer. A phase II study.

European journal of cancer (Oxford, England : 1990) • Vol. 37, Issue 3 • 2001
PMID: 11239758DOI: 10.1016/s0959-8049(00)00400-7

Changes in cell volume and internal sodium concentration in HeLa cells during exponential growth and following lonidamine treatment.

European journal of cell biology • Vol. 80, Issue 2 • 2001
PMID: 11302524DOI: 10.1078/0171-9335-00102

Documentation

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