Chemical structure of CAS 497833-27-9

Givinostat

In StockStarting at $130 for 25 mgPurity ≥ 99%
CAS No.497833-27-9
MDL No.N/A
MFC24H27N3O4
MW421.50
InChI KeyYALNUENQHAQXEA-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
25 mg99+%$130In Stock
50 mg99+%$219In Stock
100 mg99+%$369In Stock
250 mg99+%$698In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Givinostat is a naphthalene derivative substituted with ({[4-(hydroxycarbamoyl)phenyl]carbamoyl}oxy)methyl at position 2 and (diethylamino)methyl at position 6. It is a histone deacetylase inhibitor used in the treatment of Duchenne muscular dystrophy. It functions as an anti-inflammatory, angiogenesis inhibitor, antineoplastic agent, and apoptosis inducer. It is classified as a carbamate ester, tertiary amino compound, hydroxamic acid, and member of naphthalenes and benzenes. It is also the conjugate base of givinostat(1+).

CAS No.497833-27-9
Product NameGivinostat

Biological Targets

HDAC1·HDAC3·HDAC6·HDAC2·HDAC5·

Associated Conditions

polycythemia vera·Hodgkins lymphoma·Duchenne muscular dystrophy·Crohn's disease·Becker muscular dystrophy·
* The information provided here is compiled from public sources and is for reference only.