Bicuculline
| CAS No. | 485-49-4 |
|---|---|
| MDL No. | MFCD00005006 |
| MF | C20H17NO6 |
| MW | 367.40 |
| InChI Key | IYGYMKDQCDOMRE-ZWKOTPCHSA-N |
| CAS No. | 485-49-4 |
|---|---|
| MDL No. | MFCD00005006 |
| MF | C20H17NO6 |
| MW | 367.40 |
| InChI Key | IYGYMKDQCDOMRE-ZWKOTPCHSA-N |
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| 1 mg | 99% | $8 | In Stock | |
| 50 mg | 99% | $49 | In Stock | |
| 100 mg | 99% | $76 | In Stock | |
| 250 mg | 99% | $176 | In Stock | |
| 1 g | 99% | $580 | In Stock | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Bicuculline is a benzylisoquinoline alkaloid with the structure 6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinoline substituted at the 5-pro-S position by a (6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl group. It acts as a light-sensitive competitive antagonist of GABAA receptors. Originally identified in 1932 from plant alkaloid extracts, it has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. Bicuculline functions as an agrochemical, central nervous system stimulant, GABA-gated chloride channel antagonist, neurotoxin, and GABAA receptor antagonist. It belongs to the isoquinoline alkaloids and is a member of the benzylisoquinoline alkaloid class.
| CAS No. | 485-49-4 |
|---|---|
| Product Name | Bicuculline |