Chemical structure of CAS 485-49-4

Bicuculline

In StockStarting at $8 for 1 mgPurity ≥ 99%
CAS No.485-49-4
MDL No.MFCD00005006
MFC20H17NO6
MW367.40
InChI KeyIYGYMKDQCDOMRE-ZWKOTPCHSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mg99%$8In Stock
50 mg99%$49In Stock
100 mg99%$76In Stock
250 mg99%$176In Stock
1 g99%$580In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Bicuculline is a benzylisoquinoline alkaloid with the structure 6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinoline substituted at the 5-pro-S position by a (6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl group. It acts as a light-sensitive competitive antagonist of GABAA receptors. Originally identified in 1932 from plant alkaloid extracts, it has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. Bicuculline functions as an agrochemical, central nervous system stimulant, GABA-gated chloride channel antagonist, neurotoxin, and GABAA receptor antagonist. It belongs to the isoquinoline alkaloids and is a member of the benzylisoquinoline alkaloid class.

CAS No.485-49-4
Product NameBicuculline
Acute ToxicAcute Toxic
Environmental HazardEnvironmental Hazard
Signal Word:Danger
HCode:H300-H311-H331-H400
PCode:P261-P262-P264-P270-P271-P273-P280-P301+P316-P302+P352-P304+P340-P316-P321-P330-P361+P364-P391-P403+P233-P405-P501