Tofacitinib
| CAS No. | 477600-75-2 |
|---|---|
| MDL No. | MFCD22628813 |
| MF | C16H20N6O |
| MW | 312.37 |
| InChI Key | UJLAWZDWDVHWOW-YPMHNXCESA-N |
Pricing & Availability
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| - | - | On Request | On Request | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Product Information
Tofacitinib is a pyrrolopyrimidine with a pyrrolo[2,3-d]pyrimidine core substituted at position 4 by an N-methyl,N-(1-cyanoacetyl-4-methylpiperidin-3-yl)amino group. It is used as its citrate salt to treat moderately to severely active rheumatoid arthritis. It functions as an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor and an antirheumatic drug. It is also a N-acylpiperidine, a nitrile, and a tertiary amino compound.
| CAS No. | 477600-75-2 |
|---|---|
| Product Name | Tofacitinib |
Biological Targets
JAK3·JAK1·JAK2·TYK2
Associated Conditions
toxic epidermal necrolysis·extranodal nasal NK/T cell lymphoma·rheumatoid arthritis·psoriatic arthritis·chronic kidney disease·
* The information provided here is compiled from public sources and is for reference only.
