Product Information

CAS No.	475489-16-8
Product Name	NVP-AEW541

Heavy Atom Count	33	Rotatable Bond Count	7
Atom Stereo Count	0	Bond Stereo Count	0
HBA	6	HBD	1
TPSA	69.200 Å²	Charge	0
Exact Mass	439.23721	Complexity	1258.25
pKa	7.130	XLogP	4.916

Studies related to this compound and its mechanism of action

IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes.

Archives of toxicology • Vol. 91, Issue 5 • 2017

PMID: 27734117 DOI: 10.1007/s00204-016-1871-z

Insulin-like growth factor-1 boosts the developing process of condylar hyperplasia by stimulating chondrocytes proliferation.

Osteoarthritis and cartilage • Vol. 20, Issue 4 • 2012

PMID: 22281262 DOI: 10.1016/j.joca.2011.12.013

Co-administration of NVP-AEW541 and dasatinib induces mitochondrial-mediated apoptosis through Bax activation in malignant human glioma cell lines.

International journal of oncology • Vol. 37, Issue 3 • 2010

PMID: 20664932 DOI: 10.3892/ijo_00000712

Loss of Phosphatase and Tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancer.

Cancer research • Vol. 69, Issue 10 • 2009

PMID: 19435893 PMC: PMC2724871 DOI: 10.1158/0008-5472.CAN-09-0042

NVP-AEW541

CAS No.	475489-16-8
MDL No.	MFCD22741515
MF	C₂₇H₂₉N₅O
MW	439.60
InChI Key	AECDBHGVIIRMOI-UHFFFAOYSA-N

CUSTOM SYNTHESIS PRECLINICAL SUPPORT

Pricing & Availability

Pack Size	Purity	Price	Availability	Action
-	-	On Request	On Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.	475489-16-8
Product Name	NVP-AEW541

Heavy Atom Count	33	Rotatable Bond Count	7
Atom Stereo Count	0	Bond Stereo Count	0
HBA	6	HBD	1
TPSA	69.200 Å²	Charge	0
Exact Mass	439.23721	Complexity	1258.25
pKa	7.130	XLogP	4.916

NVP-AEW541

Pricing & Availability

Product Information

Properties

NVP-AEW541

Pricing & Availability

Product Information

Properties

Documentation

NVP-AEW541

Pricing & Availability

Product Information

Properties

Related Articles

IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes.

Insulin-like growth factor-1 boosts the developing process of condylar hyperplasia by stimulating chondrocytes proliferation.

Co-administration of NVP-AEW541 and dasatinib induces mitochondrial-mediated apoptosis through Bax activation in malignant human glioma cell lines.

Loss of Phosphatase and Tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancer.

NVP-AEW541

Pricing & Availability

Product Information

Properties

Related Articles

IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes.

Insulin-like growth factor-1 boosts the developing process of condylar hyperplasia by stimulating chondrocytes proliferation.

Co-administration of NVP-AEW541 and dasatinib induces mitochondrial-mediated apoptosis through Bax activation in malignant human glioma cell lines.

Loss of Phosphatase and Tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancer.

Documentation