Chemical structure of CAS 441798-33-0

Macitentan

CAS No.441798-33-0
MDL No.MFCD17167076
MFC19H20Br2N6O4S
MW588.30
InChI KeyJGCMEBMXRHSZKX-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

Macitentan is a sulfamide with the two amino groups substituted by 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl and propyl groups. It is an orphan drug used to treat pulmonary arterial hypertension. It functions as an endothelin receptor antagonist, antihypertensive agent, and orphan drug. It is an organobromine compound, a pyrimidine, aromatic ether, ring assembly, and sulfamide. It is functionally related to ethylene glycol and ACT-132577.

CAS No.441798-33-0
Product NameMacitentan

Biological Targets

EDNRB·EDNRA

Associated Conditions

congenital heart disease·pulmonary hypertension·pulmonary embolism·heart failure·hypertension·
* The information provided here is compiled from public sources and is for reference only.