Chemical structure of CAS 1103522-45-7

Aprocitentan

In StockStarting at $61 for 1 mgPurity ≥ 98%
CAS No.1103522-45-7
MDL No.MFCD28155267
MFC16H14Br2N6O4S
MW546.20
InChI KeyDKULOVKANLVDEA-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mg98%$61In Stock
5 mg98%$150In Stock
10 mg98%$181In Stock
25 mg98%$215In Stock
50 mg98%$427In Stock
100 mg98%$604In Stock
250 mg98%$896In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

ACT-132577 is a sulfamide with one amino group substituted by a 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl group. It is an active metabolite of macitentan, an orphan drug for pulmonary arterial hypertension. It functions as an antihypertensive, endothelin receptor antagonist, drug metabolite, and xenobiotic metabolite. It is an aromatic ether, organobromine compound, pyrimidine, sulfamide, and functionally related to ethylene glycol.

CAS No.1103522-45-7
Product NameAprocitentan

Biological Targets

EDNRB·EDNRA

Associated Conditions

hypertension·liver disease·kidney disease·essential hypertension
* The information provided here is compiled from public sources and is for reference only.