| CAS No. | 437982-89-3 |
|---|---|
| MDL No. | N/A |
| MF | C19H22N4O2 |
| MW | 338.40 |
| InChI Key | UAOIPNOTWOYAMU-LBPRGKRZSA-N |
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| - | - | On Request | On Request | |
| Custom synthesis and bulk supply options are available upon request. | ||||
PHA-533533 is a carboxamide formed by the formal condensation of the primary amino group of 5-cyclopropyl-1H-pyrazol-3-amine with the carboxy group of (2S)-2-phenylpropanoic acid, where the phenyl ring is substituted at the para position with a 2-oxopyrrolidin-1-yl group. It is a CDK2 inhibitor with antineoplastic activity, acting as an EC 2.7.11.22 cyclin-dependent kinase inhibitor and an antineoplastic agent. It belongs to pyrrolidin-2-ones, pyrazoles, cyclopropanes, and is a secondary and tertiary carboxamide.
| CAS No. | 437982-89-3 |
|---|---|
| Product Name | (2S)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxopyrrolidin-1-yl)phenyl]propanamide |
| Heavy Atom Count | 25 | Rotatable Bond Count | 5 |
| Atom Stereo Count | 1 | Bond Stereo Count | 0 |
| HBA | 3 | HBD | 2 |
| TPSA | 78.090 Ų | Charge | 0 |
| Exact Mass | 338.17428 | Complexity | 792.01 |
| pKa | 5.875 | XLogP | 3.156 |