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Chemical structure of CAS 38916-34-6

Cyclic somatostatin

CAS No.38916-34-6
MDL No.MFCD00076762
MFC76H104N18O19S2
MW1637.90
InChI KeyNHXLMOGPVYXJNR-ATOGVRKGSA-N

Pricing & Availability

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Product Information

Somatostatin is a fourteen-amino-acid cyclic heterodetic peptide with the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys, cyclized by a disulfide bridge between the Cys residues at positions 3 and 14. It is a peptide hormone.

CAS No.38916-34-6
Product NameCyclic somatostatin

Biological Targets

SSTR5·SSTR2·SSTR4·SSTR1·SSTR3

Associated Conditions

type 1 diabetes mellitus·liver failure·gallbladder neoplasm·gastrointestinal disease·portal hypertension·
* The information provided here is compiled from public sources and is for reference only.

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Studies related to this compound and its mechanism of action

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The Journal of experimental medicine • Vol. 202, Issue 5 • 2005
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G protein beta interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus.

The Journal of cell biology • Vol. 169, Issue 6 • 2005
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Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor-3-mediated regulation of endothelial nitric oxide synthase and mitogen-activated protein kinase activities.

Endocrinology • Vol. 144, Issue 4 • 2003
PMID: 12639942DOI: 10.1210/en.2002-220949

Somatostatin analogs in the diagnosis and treatment of cancer.

Trends in endocrinology and metabolism: TEM • Vol. 13, Issue 10 • 2002
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Documentation

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