Chemical structure of CAS 319460-85-0

Axitinib

CAS No.319460-85-0
MDL No.MFCD09837898
MFC22H18N4OS
MW386.50
InChI KeyRITAVMQDGBJQJZ-FMIVXFBMSA-N

Pricing & Availability

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Product Information

Axitinib is an indazole substituted at position 3 with a 2-(pyridin-2-yl)vinyl group and at position 6 with a 2-(N-methylaminocarboxy)phenylsulfanyl group. It is used for the treatment of advanced renal cell carcinoma following failure of first-line systemic therapy. Axitinib functions as an antineoplastic agent, tyrosine kinase inhibitor, and vascular endothelial growth factor receptor antagonist. It belongs to the classes of indazoles, pyridines, aryl sulfides, and benzamides.

CAS No.319460-85-0
Product NameAxitinib

Biological Targets

FLT1·FLT4·KDR

Associated Conditions

colorectal neoplasm·stomach neoplasm·salivary gland cancer·prostate adenocarcinoma·myelodysplastic syndrome·
* The information provided here is compiled from public sources and is for reference only.