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Chemical structure of CAS 2653994-08-0

Opnurasib

In Stock•Starting at $230 for 1 mg
CAS No.2653994-08-0
MDL No.N/A
MFC29H28ClN7O
MW526.00
InChI KeyAZUYLZMQTIKGSC-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mgTo Be Confirmed$230In Stock
5 mgTo Be Confirmed$580In Stock
10 mgTo Be Confirmed$845In Stock
25 mgTo Be Confirmed$1339In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.2653994-08-0
Product NameOpnurasib
Heavy Atom Count38Rotatable Bond Count4
Atom Stereo Count0Bond Stereo Count0
HBA6HBD1
TPSA84.630 ŲCharge0
Exact Mass525.20439Complexity1777.63
pKa5.875XLogP5.600

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Studies related to this compound and its mechanism of action

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Journal of medicinal chemistry • Vol. 65, Issue 24 • 2022
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Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C.

Cancer discovery • Vol. 12, Issue 6 • 2022
PMID: 35404998PMC: PMC9394399DOI: 10.1158/2159-8290.CD-22-0158

Documentation