| CAS No. | 253863-00-2 |
|---|---|
| MDL No. | N/A |
| MF | C22H21Cl2N5O |
| MW | 442.30 |
| InChI Key | YNBSQYGTJLIPJS-UHFFFAOYSA-N |
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| - | - | On Request | On Request | |
| Custom synthesis and bulk supply options are available upon request. | ||||
L-778,123 hydrochloride is the hydrochloride salt of L-778,123. It is a dual inhibitor of FPTase (IC50 2 nM) and GGPTase-I (IC50 98 nM), with anti-cancer properties. It functions as an antineoplastic agent, an EC 2.5.1.58 (protein farnesyltransferase) inhibitor, an EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitor, and a radiosensitizing agent. It contains the L-778,123 free base.
| CAS No. | 253863-00-2 |
|---|---|
| Product Name | 4-((5-((4-(3-Chlorophenyl)-3-oxo-1-piperazinyl)methyl)-1H-imidazol-1-yl)methyl)benzonitrile hydrochloride |
| Heavy Atom Count | 30 | Rotatable Bond Count | 5 |
| Atom Stereo Count | 0 | Bond Stereo Count | 0 |
| HBA | 5 | HBD | 0 |
| TPSA | 65.160 Ų | Charge | 0 |
| Exact Mass | 441.11232 | Complexity | 1057.89 |
| pKa | 5.875 | XLogP | 3.727 |
