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Chemical structure of CAS 2353-33-5

Decitabine

In Stock•Starting at $8 for 1 mg•Purity ≥ 98%
CAS No.2353-33-5
MDL No.MFCD00043011
MFC8H12N4O4
MW228.21
InChI KeyXAUDJQYHKZQPEU-KVQBGUIXSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mg99%$8In Stock
10 mg99%$9In Stock
100 mg98%$12In Stock
250 mg98%$21In Stock
1 g98%$52In Stock
5 g98%$233In Stock
10 g98%$386In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

5-Aza-2'-deoxycytidine is a 2'-deoxyribonucleoside.

CAS No.2353-33-5
Product NameDecitabine

Biological Targets

DNMT1·DNMT3A

Associated Conditions

myeloid leukemia·neoplasm of mature B-cells·acute lymphoblastic leukemia·ovarian cancer·chronic myelomonocytic leukemia·
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Evidence that silencing of the HPRT promoter by DNA methylation is mediated by critical CpG sites.

The Journal of biological chemistry • Vol. 276, Issue 1 • 2001
PMID: 11013250DOI: 10.1074/jbc.M007096200

Biallelic inactivation of retinoic acid receptor beta2 gene by epigenetic change in breast cancer.

The American journal of pathology • Vol. 158, Issue 1 • 2001
PMID: 11141504PMC: PMC1850266DOI: 10.1016/s0002-9440(10)63969-7

Site-specific methylation of the promoter alters deoxyribonucleic acid-protein interactions and prevents follicle-stimulating hormone receptor gene transcription.

Biology of reproduction • Vol. 64, Issue 2 • 2001
PMID: 11159363DOI: 10.1095/biolreprod64.2.602

Sensitization by 5-aza-2'-deoxycytidine of leukaemia cells with MLL abnormalities to induction of differentiation by all-trans retinoic acid and 1alpha,25-dihydroxyvitamin D3.

British journal of haematology • Vol. 112, Issue 2 • 2001
PMID: 11167824DOI: 10.1046/j.1365-2141.2001.02523.x

Documentation

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