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Chemical structure of CAS 223645-67-8

Ripasudil

CAS No.223645-67-8
MDL No.MFCD28291829
MFC15H18FN3O2S
MW323.40
InChI KeyQSKQVZWVLOIIEV-NSHDSACASA-N

Pricing & Availability

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Product Information

Ripasudil is an isoquinoline compound.

CAS No.223645-67-8
Product NameRipasudil

Biological Targets

ROCK2·ROCK1

Associated Conditions

Fuchs' endothelial dystrophy·glaucoma·corneal edema·retinopathy of prematurity·Fuchs endothelial corneal dystrophy
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm's canal endothelial cells.

Scientific reports • Vol. 6 • 2016
PMID: 26782355PMC: PMC4725980DOI: 10.1038/srep19640

Effects of K-115, a rho-kinase inhibitor, on aqueous humor dynamics in rabbits.

Current eye research • Vol. 39, Issue 8 • 2014
PMID: 24502505DOI: 10.3109/02713683.2013.874444

Ripasudil: first global approval.

Drugs • Vol. 74, Issue 18 • 2014
PMID: 25414122DOI: 10.1007/s40265-014-0333-2

Phase 1 clinical trials of a selective Rho kinase inhibitor, K-115.

JAMA ophthalmology • Vol. 131, Issue 10 • 2013
PMID: 23787820DOI: 10.1001/jamaophthalmol.2013.323

Documentation

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