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Chemical structure of CAS 222727-43-7

Fluciclovine

In Stock•Starting at $568 for 100 mg•Purity ≥ 97%
CAS No.222727-43-7
MDL No.MFCD23106395
MFC5H8FNO2
MW133.12
InChI KeyNTEDWGYJNHZKQW-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
100 mg97%$568In Stock
250 mg97%$906In Stock
500 mg97%$1508In Stock
1 g97%$2259In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Fluciclovine is a cyclobutane derivative with carboxy, amino, and fluoro groups at positions 1, 1, and 3, respectively (the 1R,3R-stereoisomer). It is an alpha-amino acid, a fluoroamino acid, a monocarboxylic acid, and a primary amino compound.

CAS No.222727-43-7
Product NameFluciclovine

Associated Conditions

glioblastoma multiforme·prostate cancer·nasopharyngeal carcinoma·metastatic prostate cancer·invasive lobular carcinoma·
* The information provided here is compiled from public sources and is for reference only.

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Studies related to this compound and its mechanism of action

Detection of recurrent prostate carcinoma with anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid PET/CT and 111In-capromab pendetide SPECT/CT.

Radiology • Vol. 259, Issue 3 • 2011
PMID: 21493787PMC: PMC3099047DOI: 10.1148/radiol.11102023

Phase I clinical study of NMK36: a new PET tracer with the synthetic amino acid analogue anti-[18F]FACBC.

Annals of nuclear medicine • Vol. 25, Issue 6 • 2011
PMID: 21409348DOI: 10.1007/s12149-011-0477-z

Putative transport mechanism and intracellular fate of trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid in human prostate cancer.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine • Vol. 52, Issue 5 • 2011
PMID: 21536930DOI: 10.2967/jnumed.110.086074

Synthesis and biological evaluation of anti-1-amino-2-[18F]fluoro-cyclobutyl-1-carboxylic acid (anti-2-[18F]FACBC) in rat 9L gliosarcoma.

Bioorganic & medicinal chemistry letters • Vol. 20, Issue 7 • 2010
PMID: 20207538DOI: 10.1016/j.bmcl.2010.02.048

Documentation

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